Life is intrinsically pointless since meaning is something we assign to things; like a task is only meaningful when it serves a desirable goal. Not just any goal, the intention to achieve it has to be present in order to make it worthwhile. Intention is the key to meaning.
Since meaning is something we assign to things through intention, a meaningful life is one intentionally lived. This doesn’t mean having complete control over it, this is impossible since life is unpredictable and the majority of forces influencing your life are out of your control. However it does mean acting intentionally, setting goals to strive towards, and taking steps to achieve them. Roadblocks will always show up, if you are living intentionally you respond by finding other roads and picking yourself up when you trip and fall. It means consciously deciding what you want to do with your life, not just reacting to whatever happens to you.
Our actions define us. And, as I pointed out earlier, our actions are our real choices. In the end it’s not about what happened to us but how we reacted to it. What defines us, and how meaningful our life was, is how we decided to live it by the actions we took.